Doutor/livre docente

Int. J. Oral Maxillofac. Surg. 2004; 33: 621–624 doi:10.1016/j.ijom.2003.10.019, available online at http://www.sciencedirect.com

Case Report Clinical Pathology

Sialadenoma papilliferum: immunohistochemical study
´ A. P. N. Gomes, A. P. V. Sobral, S. V. L. Loducca, V. C. de Araujo:Sialadenoma papilliferum: immunohistochemical study. Int. J. Oral Maxillofac. Surg. 2004; 33: 621–624. # 2004 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
Abstract. Sialadenoma papilliferum (SP) is a rare benign tumour of salivary gland origin, which has been included among the ductal papillomas in the latest classification of tumours by the World Health Organisation. Two SP from the minor salivary gland of the palate of middle age patients were presented and studied by immunohistochemical. Our results showed presence of cytokeratins (CKs) 13, 14, 7, 8, 19 and absence of vimentin and smooth muscle actin. This immunoprofile is similar to the excretory duct of salivary gland.

A. P. N. Gomes1, A. P. V. Sobral2, ´ S. V. L. Loducca3, V. C. de Araujo3
1 Department of Oral Pathology, School of Dentistry, University of Pelotas, Pelotas, Brazil; 2Department of Oral Pathology, School of Dentistry, University of Pernambuco, Pernambuco, Brazil; 3Department of Oral Pathology, School of Dentistry, Faculdade de ˜ Odontologia, University of Sao Paulo, Av. Prof Lineu Prestes, 2227, CEP: 05508-900, ˜ Sao Paulo, SP Brazil ,

Key words: salivary gland tumours; sialadenoma papilliferum; ductal papillomas; cytokeratin. Accepted for publication 17 October 2003 Available online 6 February 2004

Sialadenoma papilliferum (SP) is a rare benign tumour of salivary gland origin first reported in the literature by ABRAMS & FINCK in 19691. This name was proposed based on its gross and microscopic appearances, which closely resembled those of the syringocystadenoma papilliferum of the sweat gland. The tumour, which has been included among the