Desenvolvimento neuropsicomotor
Sven Gläser, Christian F. Opitz, Ulrike Bauer, Roland Wensel, Ralf Ewert, Peter E. Lange and Franz Xaver Kleber Chest 2004;125;368-376 DOI 10.1378/chest.125.2.368
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clinical investigations
Assessment of Symptoms and Exercise Capacity in Cyanotic Patients With Congenital Heart Disease*
Sven Glaser, MD; Christian F. Opitz, MD; Ulrike Bauer, MD; ¨ Roland Wensel, MD; Ralf Ewert, MD; Peter E. Lange, MD; and Franz Xaver Kleber, MD
Objectives: Patients with cyanotic congenital heart disease are generally thought to be limited by hypoxemia. To correlate exercise tolerance to the severity of the cardiac abnormality and to further characterize dyspnea in affected patients, we examined 25 adults with uncorrected cyanotic congenital heart disease. Design and setting: Cohort study at a university hospital. Methods: Symptom-limited cardiopulmonary exercise testing (CPX) was performed on a treadmill. Expiratory gas was analyzed breath by breath for evaluation of maximal exercise performance, ventilation, and ventilatory efficiency in combination with blood gas analysis during rest and exercise. Symptoms were assessed by the ability index and New York