SOMOS CONTRA A EUTANASIA

ARTIGO ARTICLE

Riscos ocupacionais para o câncer de laringe: um estudo caso-controle
Occupational risks for laryngeal cancer: a case-control study

Sergio Guerra Sartor 1
José Eluf-Neto 1
Noemie Travier 2
Victor Wünsch Filho 3
Arline Sydneia Abel Arcuri 4
Luís Paulo Kowalski 5
Paolo Boffetta 2

Abstract
Faculdade de Medicina,
Universidade de São Paulo,
São Paulo, Brasil.
2 Unit of Environmental
Cancer Epidemiology,
International Agency for
Research on Cancer,
Lyon, France.
3 Faculdade de Saúde
Pública, Universidade de
São Paulo, São Paulo, Brasil.
4 Fundação Jorge Duprat
Figueiredo de Segurança e
Medicina do Trabalho,
São Paulo, Brasil.
5 Centro de Tratamento e
Pesquisa, Hospital do Câncer
A. C. Camargo, São Paulo,
Brasil.
1

Correspondência
S. G. Sartor
Departamento de Medicina
Preventiva, Faculdade de
Medicina, Universidade de
São Paulo.
Av. Dr. Arnaldo 455, 2 o andar,
São Paulo, SP
01246-903, Brasil. [e-mail] Introdução

The most solidly established risk factors for laryngeal cancer are tobacco and alcohol. As for occupational factors, the only established carcinogen is exposure to strong inorganic acid mists. However, asbestos, pesticides, paints, gasoline, diesel engine emissions, dusts, and other factors have been reported in the literature as occupational agents that increase the risk of laryngeal cancer. A hospital-based case-control study was conducted to investigate occupational risk factors for laryngeal cancer. Detailed data on smoking, alcohol consumption, and occupational history were collected for 122 laryngeal cancers and 187 controls matched by frequency
(according to sex and age). Laryngeal cancer was associated with exposure to respirable free crystalline silica (OR = 1.83; 95%CI: 1.00-3.36), soot
(from coal, coke, fuel oil, or wood) (odds ratio
– OR = 1.78; 95% confidence interval – 95%CI:
1.03-3.03), fumes (OR = 2.55; 95%CI: 1.14-5.67), and live animals (OR = 1.80; 95%CI: