Oficinas

4244 palavras 17 páginas
Revista da Sociedade Brasileira de Medicina Tropical
Print version ISSN 0037-8682
Rev. Soc. Bras. Med. Trop. vol.42 no.3 Uberaba May/June 2009 http://dx.doi.org/10.1590/S0037-86822009000300001 ARTICLE ARTIGO
Hepatitis C: sexual or intrafamilial transmission? Epidemiological and phylogenetic analysis of hepatitis C virus in 24 infected couples
Hepatite C: transmissão sexual ou intrafamiliar? Análise epidemiológica e filogenética do vírus da hepatite C em 24 casais infectados
Norma de Paula CavalheiroI; Abel De La RosaII; Slava ElaginIII; Fátima Mitiko TenganI; Evaldo Stanislau Affonso de AraújoI; Antonio Alci BaroneI
IHepatitis Laboratory, Medical School, University of São Paulo, SP, Brazil
IIPharmasset Inc, Atlanta, Georgia, USA
IIIThird Wave Molecular Diagnostics, Madison, Wisconsin, USA
Address to
ABSTRACT
The role of sexual or intrafamilial transmission of hepatitis C is controversial. A phylogenetic analysis was performed on the non-structural region 5B of the hepatitis C virus (NS5B-HCV). High percentages of homology (mean of 98.3%) were shown between the couples. Twenty (83.3%) of the 24 men but only two of the women (8.3%) reported having had sexually transmitted diseases during their lives. The risk factors for HCV acquisition were blood transfusion (10 couples), use of illegal injected drugs (17), use of inhalants (15), acupuncture (5) and tattoos (5). The shared use of personal hygiene items included toothbrushes between six couples (25%), razor blades between 16 (66.7%), nail clippers between 21 (87.5%) and manicure pliers between 14 (58.3%). The high degree of similarity of the hepatitis C virus genome supports the hypothesis of hepatitis C virus transmission between these couples. The shared use of personal hygiene items suggests the possibility of intrafamilial transmission of infection.
Key-words: Intrafamilial. Hepatitis C virus. Sexual transmission. Heterosexual. Phylogeny.

RESUMO
O papel da transmissão sexual ou intrafamiliar

Relacionados

  • Oficinas
    659 palavras | 3 páginas
  • oficina
    1663 palavras | 7 páginas
  • oficinas
    265 palavras | 2 páginas
  • oficina
    1444 palavras | 6 páginas
  • oficina
    902 palavras | 4 páginas
  • oficina
    564 palavras | 3 páginas
  • Oficina
    335 palavras | 2 páginas
  • oficina
    878 palavras | 4 páginas
  • Oficina
    779 palavras | 4 páginas
  • oficina
    967 palavras | 4 páginas