Bone marrow

Bone Marrow

Mariana Gianezi

Introduction
• Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis.

Marrow Types
• Medulla ossium rubra (red marrow), which consists mainly of hematopoietic tissue.

• Medulla ossium flava (yellow marrow), which is mainly made up of fat cells.

Curiosity
• At birth, all bone marrow is red. With age, more and more of it is converted to the yellow type; only around half of adult bone marrow is red

 In cases of severe blood loss, the body can convert yellow marrow back to red marrow to increase blood cell production

Why do you need a transplant ?

• Bone Marrow
Transplantation (BMT) is primarily indicated for the treatment of disorders that impair the function of bone marrow as hematological diseases, onco-hematology, immunodeficiency diseases, genetic damage, some solid tumors and autoimmune diseases.

hematological diseases

onco-hematology

immunodeficiency

genetic damage

If you decide to donate…
1st. You must be between 18 and 55 years of age and be in good general health
2nd. You can register as a volunteer donor bone marrow transfusion centers in your state. 3rd. It will be removed from your vein a small amount of blood (5ml) and filled in a form with personal information.
 Your blood will be typified by examination of histocompatibility
 Its data are crossed with those of patients requiring bone marrow transplantation constantly  If compatibility is confirmed, you will be asked to confirm you want to make a donation. Your current health status will be assessed.
 The donation is a procedure that is done in the operating room under general or epidural anesthesia, and requires hospitalization for a minimum of 24 hours.
Important: A bone marrow donor must keep your records updated whenever possible. If there is any change, please complete this