Neurotoxin

in nociceptive processing in the rat spinal cord: results from behavioural and electrophysiological studies. Neurosci Lett 1996; 208: 203 – 7 2 Allen JW, Mantyh PW, Horais K, et al. Safety evaluation of intrathecal substance P-saporin, a targeted neurotoxin, in dogs. Toxicol Sci 2006; 91: 286 – 98 3 Backonja M, Beydoun A, Edwards KR, et al. Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial. JAMA 1998; 280:…

Bruxinhas de Deus: a Serviço da Vida. Porto Alegre: Evangraf. 50p. DUKE, J. 1985. CRC Handbook of Medicinal Herbs. Boca Raton: CRC. 677p. DUNCAN, M. W., KOPIN, I. J., CROWLEY, J. S., JONES, S. M. & MARKEY, S. P. 1989. Quantification of the putative neurotoxin 2-amino3-(methylamino)propanoic acid (BMAA) in cycadales: analysis of the seeds of some members of the family Cycadaceae. Journal of Analytical Toxicology, 13(4): suppl. A-G. DUNCAN, M. W., STEELE, J. C., KOPIN, I. J. & MARKEY, S.…

effectiveness of exercise interventions for people with Parkinson’s disease: a systematic review and metaanalysis. Mov Disord. 2008;23(5):631-40. S215 44. Nguyen N, Lee SB, Lee YS, Lee KH, Ahn JY. Neuroprotection by NGF and BDNF Against Neurotoxin-Exerted Apoptotic Death in Neural Stem Cells Are Mediated Through Trk Receptors, Activating PI3-Kinase and MAPK Pathways. Neurochem Res. 2009;34(5):942-51. 45. Mattson MP, Gleichmann M, Cheng A. Mitochondria in neuroplasticity and…

2002). The astroglial glutamate transporters GLAST (EAAT1) and GLT1 (EAAT2) are mainly responsible for the clearance of extracellular glutamate (Rothstein et al., 1996; Danbolt, 2001). Besides its physiological effects, glutamate is also a potent neurotoxin and the presence of high amounts of this neurotransmitter in the synaptic cleft may lead to excitotoxicity by over-stimulation of glutamate receptors, a process related to neuropathology of acute (brain hypoxia, ischemia and…

coenzyme Q reductase) is made up of 41 different polypeptides and can oxidize NADH. It pumps protons out of the mitochondrion, contributing to the proton electrochemical gradient, and can lead to ROS generation. This complex is inhibited by the neurotoxin 1-methyl-4-phenylpyridine (MPP+), by rotenone and by nitric oxide. Complex II (succinate: ubiquinone reductase), which is composed of four proteins, catalyzes the oxidation of succinate to fumarate, with the formation of ubiquinol from…

Botox (www.wemove.org). 8. for Cervical Dystonia. Toxins’99 Hauser RA, Comella C, Brashear A, Truong D, Charles PD, Tsui J. A Randomized, Multicenter, Placebo-Controlled Study of Original Botox (Botulinum Toxin Type A) Purified Neurotoxin Complex for the Treatment of Cervical Dystonia. Movement Disorders 2000;15 Suppl 2:30. Gelb 1989 {published data only} Gelb DJ, Arbor A, Don M. Yoshimura RKO, Lowenstein DH, Aminoff MJ. Change in Pattern of Muscle Activity…

salve for infected and necrotic wounds, and inhibitor of tumor growth. The rhizome of the plant contains a resin, known generally and commercially as Indian Podophyllum Resin, which can be processed to extract podophyllotoxin or podophyllin, a neurotoxin. Podophyllotoxin is the major lignan present in the resin and is a dimerized product of the intermediates of the phenylpropanoid pathway. The starting material of etoposide (Vepeside), an FDA approved anticancer drug is…

frequency of spontaneous firing in intact C-fiber nociceptors. J Neurosci 2006;26(4):1281-92. http://pesquisa.bvsalud.org/regional/resources/mdl-16436616 155. Luvisetto S, Marinelli S, Cobianchi S, et al. Anti-allodynic efficacy of botulinum neurotoxin A in a model of neuropathic pain. Neuroscience 2007;145(1):1-4. http://pesquisa.bvsalud.org/regional/resources/mdl-17218063 156. Ranoux D, Attal N, Morain F, et al. Botulinum toxin type A induces direct analgesic effects in…

frequency of spontaneous firing in intact C-fiber nociceptors. J Neurosci 2006;26(4):1281-92. http://pesquisa.bvsalud.org/regional/resources/mdl-16436616 155. Luvisetto S, Marinelli S, Cobianchi S, et al. Anti-allodynic efficacy of botulinum neurotoxin A in a model of neuropathic pain. Neuroscience 2007;145(1):1-4. http://pesquisa.bvsalud.org/regional/resources/mdl-17218063 156. Ranoux D, Attal N, Morain F, et al. Botulinum toxin type A induces direct analgesic effects in…

BOL beginning of life [pacemaker battery] BOLO bleomycin, Oncovin, lomustine, dacarbazine; blood oxygennation leveI dependent BolVX Boletus virus X BOM bilateral otitis media BOMA bilateral otitis media, acute BoNT A, B, C, D, E botulinum neurotoxin A, B, C, D, and E BOOP bronchiolitis obliterans-organizing pneumonia BOP buffalo orphan prototype [virus] BOPP boronated protoporphyrin BOR basal optic root; before time of operation; bowels open regularly; branchio-otorenal…